The PoppiE Study

Can you help us find out the ideal amount of iodine needed in pregnancy for baby’s brain development?

Who can take part?

  • Pregnant women who are less than 13 weeks into their pregnancy

Check your eligibility

Why are we interested in iodine in pregnancy?

Getting the right amount of iodine in pregnancy is important for baby’s brain and nervous system development. Since 2009, iodine has been added to some of our food and pregnant women are also advised to take a supplement containing iodine. Recent studies suggest that some women get enough iodine from the food they eat and may not need the amount of iodine that is contained in common prenatal supplements. The South Australian Health and Medical Research Institute (SAHMRI) is working with colleagues around Australia to find out the optimal level of iodine supplementation for pregnant women who already have an adequate iodine intake from the food that they eat.

What does the PoppiE Study involve?

We will supply 754 pregnant women from around Australia with prenatal supplements to take during pregnancy. Half of the supplements will contain the common amount of iodine found in prenatal supplements in Australia and the other half will contain a reduced amount of iodine. We will only include women who already have an adequate intake of iodine from their diet which we will assess by an ‘iodine food frequency questionnaire’.

Once the babies in the PoppiE trial reach 2 years of age, they will receive an in-depth developmental assessment at one of our participating research centres. We will compare the results of these assessments between the ‘standard iodine supplement’ and ‘low iodine supplement’ groups.

Why should you take part?

  • You will receive prenatal supplements for the whole of your pregnancy at no charge.
  • You will know your iodine status from food by completing our Iodine Food Frequency Questionnaire (iFFQ).
  • You will be reimbursed for attendance at the 24-month developmental assessment with your child and you will receive a report of their assessment.
  • You will help contribute valuable information that may benefit other pregnant women and their babies in the future.


  Check your eligibility

The PoppiE Study is being led by Dr Karen Best and managed from the South Australian Health and Medical Research Institute (SAHMRI).

We are working together with our colleagues in the following centres*.

  • Women’s and Children’s Hospital, South Australia
  • Flinders Medical Centre, South Australia
  • Mater Mothers’ Hospital, Queensland
  • The Royal Women’s Hospital, Victoria
  • Royal North Shore Hospital, New South Wales

*You do not need to be having your baby at one of these centres to take part.

Contact us

For further information please contact one of the PoppiE Research team:

Funding and Ethics

  • The PoppiE Study is funded by the Australian Government, Medical Research Futures Fund (MRFF).
  • This study has been reviewed and approved by Women’s and Children’s Health Network (WCHN) Ethics Committee
Get in touch
+61 8 8128 4000 info@sahmri.com
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North Terrace Adelaide 5000 South Australia
Postal Address
PO BOX 11060 Adelaide 5001 South Australia
Key Partners
SAHMRI is located on the traditional lands of the Kaurna Nation.

The SAHMRI community acknowledges and respects the traditional owners, the family clans who are the Kaurna Nation from the Adelaide Plains region of South Australia. We acknowledge the clans of the Kaurna Nation and the sacred knowledge they hold for their country. We pay our respects to the Kaurna Nation, their ancestors and the descendants of these living family clans today.